Standard Name	GPT2 (see Nomenclature conflict Note)
Systematic Name	YKR067W
Alias	GAT1 1
Feature Type	ORF, Verified
Description	Glycerol-3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase located in lipid particles and the ER; involved in the stepwise acylation of glycerol-3-phosphate and dihydroxyacetone in lipid biosynthesis; the most conserved motifs and functionally relevant residues are oriented towards the ER lumen (1, 2, 3, 4)
Name Description	Glycerol-3-Phosphate acylTransferase

Chromosomal Location	ChrXI:567918 to 570149 | ORF Map | GBrowse

	View Computational GO annotations for GPT2
Molecular Function
Manually curated	glycerol-3-phosphate O-acyltransferase activity (IDA, IGI, IMP) glycerone-phosphate O-acyltransferase activity (IDA)
Biological Process
Manually curated	phospholipid biosynthetic process (IDA, IGI, IMP)
Cellular Component
Manually curated	endoplasmic reticulum (IDA) lipid particle (IDA)
High-throughput	cytoplasm (IDA) endoplasmic reticulum (IDA) integral to membrane (ISM)

Pathways	phosphatidate biosynthesis I (the dihydroxyacetone pathway) phosphatidate biosynthesis II (the glycerol-3-phosphate pathway) superpathway of phosphatidate biosynthesis

Classical genetics
null	cell shape: abnormal resistance to oleate: decreased
Large-scale survey
null	competitive fitness: increased haploinsufficient resistance to oleate: decreased viable
overexpression	cell cycle progression: abnormal
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	133 total interaction(s) for 98 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 1 PCA: 2
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 100 Phenotypic Suppression: 1 Positive Genetic: 17 Synthetic Growth Defect: 4 Synthetic Lethality: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXI:567918 to 570149 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2232 567918..570149 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001775