TRK2/YKR050W Summary Help

Standard Name TRK2 1, 2
Systematic Name YKR050W
Alias RPD2
Feature Type ORF, Verified
Description Component of the Trk1p-Trk2p potassium transport system; contributes to K(+) supply and maintenance of plasma-membrane potential; TRK2 has a paralog, TRK1, that arose from the whole genome duplication (1, 3, 4, 5)
Name Description TRansport of potassium (K)
Chromosomal Location
ChrXI:527815 to 530484 | ORF Map | GBrowse
Gbrowse
Genetic position: 15 cM
Gene Ontology Annotations All TRK2 GO evidence and references
  View Computational GO annotations for TRK2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 8 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
84 total interaction(s) for 40 unique genes/features.
Physical Interactions
  • PCA: 3

Genetic Interactions
  • Dosage Lethality: 3
  • Dosage Rescue: 7
  • Negative Genetic: 11
  • Phenotypic Enhancement: 12
  • Phenotypic Suppression: 9
  • Positive Genetic: 1
  • Synthetic Growth Defect: 19
  • Synthetic Lethality: 4
  • Synthetic Rescue: 15

Resources
Expression Summary
histogram
Resources
Length (a.a.) 889
Molecular Weight (Da) 101,086
Isoelectric Point (pI) 10.36
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:527815 to 530484 | ORF Map | GBrowse
SGD ORF map
Genetic position: 15 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2670 527815..530484 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000001758
References cited on this page View Complete Literature Guide for TRK2
1) Ko CH, et al.  (1990) TRK2 is required for low affinity K+ transport in Saccharomyces cerevisiae. Genetics 125(2):305-12
2) Petitjean, A. and Tatchell, K.  (1989) Personal Communication, Mortimer Map Edition 10
3) Ko CH and Gaber RF  (1991) TRK1 and TRK2 encode structurally related K+ transporters in Saccharomyces cerevisiae. Mol Cell Biol 11(8):4266-73
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5) Petrezselyova S, et al.  (2011) Trk2 transporter is a relevant player in K+ supply and plasma-membrane potential control in Saccharomyces cerevisiae. Folia Microbiol (Praha) 56(1):23-8