UTH1/YKR042W Summary Help

UTH1 BASIC INFORMATION

Standard Name UTH1
Systematic Name YKR042W
Feature Type ORF, Verified
Description Mitochondrial outer membrane and cell wall localized SUN family member required for mitochondrial autophagy; involved in the oxidative stress response, life span during starvation, mitochondrial biogenesis, and cell death (1, 2, 3, 4, 5, 6)
Name Description yoUTH 1, 7
GO Annotations All UTH1 GO evidence and references
    View Computational GO annotations for UTH1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All UTH1 Phenotype details and references
Classical genetics
null
unspecified
Large-scale survey
null
Interactions UTH1 All interactions details and references
13 total interaction(s) for 11 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
Genetic Interactions
  • Phenotypic Enhancement: 2
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 5
  • Synthetic Rescue: 1
Sequence Information
ChrXI:519169 to 520266 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2005-12-15 | Sequence: 2005-11-03
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1098 519169..520266 2005-12-15 2005-11-03
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001750

UTH1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for UTH1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for UTH1]

1) Kennedy BK, et al.  (1995) Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae. Cell 80(3):485-96
2) Bandara PD, et al.  (1998) Involvement of the Saccharomyces cerevisiae UTH1 gene in the oxidative-stress response. Curr Genet 34(4):259-68
3) Camougrand NM, et al.  (2000) The "SUN" family: UTH1, an ageing gene, is also involved in the regulation of mitochondria biogenesis in Saccharomyces cerevisiae. Arch Biochem Biophys 375(1):154-60
4) Velours G, et al.  (2002) Dual cell wall/mitochondria localization of the 'SUN' family proteins. FEMS Microbiol Lett 207(2):165-72
5) Kissova I, et al.  (2004) Uth1p is involved in the autophagic degradation of mitochondria. J Biol Chem 279(37):39068-74
6) Camougrand N, et al.  (2003) The product of the UTH1 gene, required for Bax-induced cell death in yeast, is involved in the response to rapamycin. Mol Microbiol 47(2):495-506
7) Austriaco NR Jr  (1996) Review: to bud until death: the genetics of ageing in the yeast, Saccharomyces. Yeast 12(7):623-30