SPO14/YKR031C Summary Help

SPO14 BASIC INFORMATION

Standard Name SPO14 1
Systematic Name YKR031C
Alias PLD1
Feature Type ORF, Verified
Description Phospholipase D, catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid; involved in Sec14p-independent secretion; required for meiosis and spore formation; differently regulated in secretion and meiosis (2, 3, 4, 5)
Name Description SPOrulation
GO Annotations All SPO14 GO evidence and references
    View Computational GO annotations for SPO14
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Pathways
Mutant Phenotype All SPO14 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions SPO14 All interactions details and references
31 total interaction(s) for 20 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-Western: 2
  • Co-localization: 2
  • Two-hybrid: 1
Genetic Interactions
  • Dosage Rescue: 3
  • Phenotypic Enhancement: 3
  • Phenotypic Suppression: 4
  • Synthetic Growth Defect: 5
  • Synthetic Lethality: 8
Sequence Information
ChrXI:506037 to 500986 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 18 cM
Last Update Coordinates: 2005-12-15 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..5052 506037..500986 2005-12-15 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001739

SPO14 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SPO14

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SPO14]

1) Townsend, M., et al.  (1985) Personal Communication, Mortimer Map Edition 9
2) Xie Z, et al.  (1998) Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects. Proc Natl Acad Sci U S A 95(21):12346-51
3) Sreenivas A, et al.  (1998) A role for phospholipase D (Pld1p) in growth, secretion, and regulation of membrane lipid synthesis in yeast. J Biol Chem 273(27):16635-8
4) Rudge SA, et al.  (1998) Relocalization of phospholipase D activity mediates membrane formation during meiosis. J Cell Biol 140(1):81-90
5) Rudge SA, et al.  (2002) Differential regulation of Saccharomyces cerevisiae phospholipase D in sporulation and Sec14-independent secretion. Genetics 160(4):1353-61