DBP7/YKR024C Summary Help

Standard Name DBP7 1
Systematic Name YKR024C
Feature Type ORF, Verified
Description Putative ATP-dependent RNA helicase of the DEAD-box family; involved in ribosomal biogenesis; required at post-transcriptional step for efficient retrotransposition; essential for growth under anaerobic conditions (1, 2, 3)
Name Description Dead Box Protein 1
Chromosomal Location
ChrXI:487372 to 485144 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All DBP7 GO evidence and references
  View Computational GO annotations for DBP7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
null
repressible
Large-scale survey
null
Resources
135 total interaction(s) for 127 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 28
  • Affinity Capture-Western: 2
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 84
  • Positive Genetic: 9
  • Synthetic Growth Defect: 8
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 742
Molecular Weight (Da) 83,308
Isoelectric Point (pI) 10.04
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:487372 to 485144 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2229 487372..485144 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001732
References cited on this page View Complete Literature Guide for DBP7
1) Daugeron MC and Linder P  (1998) Dbp7p, a putative ATP-dependent RNA helicase from Saccharomyces cerevisiae, is required for 60S ribosomal subunit assembly. RNA 4(5):566-81
2) Ishtar Snoek IS and Yde Steensma H  (2006) Why does Kluyveromyces lactis not grow under anaerobic conditions? Comparison of essential anaerobic genes of Saccharomyces cerevisiae with the Kluyveromyces lactis genome. FEMS Yeast Res 6(3):393-403
3) Risler JK, et al.  (2012) Host co-factors of the retrovirus-like transposon Ty1. Mob DNA 3(1):12