Standard Name	DBP7 1
Systematic Name	YKR024C
Feature Type	ORF, Verified
Description	Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis; essential for growth under anaerobic conditions (1, 2)
Name Description	Dead Box Protein 1

Chromosomal Location	ChrXI:487372 to 485144 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for DBP7
Molecular Function
Manually curated	ATP-dependent RNA helicase activity (ISS)
Biological Process
Manually curated	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (IMP)
Cellular Component
Manually curated	nucleolus (IDA)

Classical genetics
null	cold sensitivity: increased resistance to tellurite: decreased vegetative growth: decreased rate vegetative growth: decreased viable
repressible	vegetative growth: decreased
Large-scale survey
null	bud morphology: abnormal cell size: increased competitive fitness: decreased dessication resistance: decreased fermentative growth: decreased rate haploinsufficient heat sensitivity: increased Fus-Mid-GFP distribution: abnormal resistance to amiodarone: decreased resistance to spermine: increased resistance to sodium arsenite: increased resistance to hydroxyurea: increased resistance to nickel(2+): increased resistance to cycloheximide: decreased resistance to paromomycin: decreased resistance to hygromycin B: decreased resistance to ethanol: decreased resistance to pentachlorophenol: decreased resistance to 5-fluorouracil: decreased resistance to benzo[a]pyrene: decreased resistance to L-1,4-dithiothreitol: decreased resistance to doxorubicin: decreased stress resistance: increased toxin resistance: increased vacuolar morphology: abnormal vegetative growth: decreased rate vegetative growth: absent viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	134 total interaction(s) for 127 unique genes/features.
Physical Interactions	Affinity Capture-MS: 27 Affinity Capture-Western: 2 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 84 Positive Genetic: 9 Synthetic Growth Defect: 8 Synthetic Lethality: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXI:487372 to 485144 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2229 487372..485144 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001732