SRY1/YKL218C Summary

SRY1 BASIC INFORMATION

Standard Name	SRY1
Systematic Name	YKL218C
Feature Type	ORF, Verified
Description	3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required in the presence of hydroxyaspartate; highly similar to mouse serine racemase (Srr) but has no serine racemase activity (1)
Name Description	Serine Racemase of Yeast 1

GO Annotations	All SRY1 GO evidence and references
	View Computational GO annotations for SRY1
Molecular Function
Manually curated	NOT serine racemase activity (IDA, IMP) threo-3-hydroxyaspartate ammonia-lyase activity (IDA, IMP)
Biological Process
Manually curated	cellular amino acid derivative catabolic process (IDA, IMP)
Cellular Component
Manually curated	cellular_component unknown (ND)

Mutant Phenotype	All SRY1 Phenotype details and references
Classical genetics
null	resistance to 3-hydroxyaspartate: decreased resistance to D-serine: normal
Large-scale survey
null	competitive fitness: increased viable

Interactions	SRY1 All interactions details and references
	View additional details at BioGRID
	104 total interaction(s) for 82 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 1 Two-hybrid: 2
Genetic Interactions	Negative Genetic: 94 Positive Genetic: 6

Sequence Information

ChrXI:18339 to 17359 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..981	18339..17359	1996-07-31	1996-07-31

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001701

SRY1 RESOURCES

Click on map for expanded view

SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for SRY1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SRY1]

1)	Wada M, et al. (2003) Serine racemase homologue of Saccharomyces cerevisiae has L-threo-3-hydroxyaspartate dehydratase activity. FEMS Microbiol Lett 225(2):189-93

SGD^tm pages Database Copyright © 1997-2010 The Board of Trustees of Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. The SGD project at Stanford University is supported by a Genome Research Resource Grant from the US National Human Genome Research Institute, part of the US National Institutes of Health.