TRP3/YKL211C Summary Help

Standard Name TRP3 1
Systematic Name YKL211C
Feature Type ORF, Verified
Description Indole-3-glycerol-phosphate synthase; forms bifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p (2, 3, 4, 5)
Name Description TRyPtophan requiring
Chromosomal Location
ChrXI:38153 to 36699 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: -153.8 cM
Gene Ontology Annotations All TRP3 GO evidence and references
  View Computational GO annotations for TRP3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Pathways
Classical genetics
null
unspecified
Large-scale survey
null
Resources
71 total interaction(s) for 58 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 26
  • Co-purification: 1
  • Reconstituted Complex: 7
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 30
  • Positive Genetic: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 484
Molecular Weight (Da) 53,489
Isoelectric Point (pI) 6.9
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:38153 to 36699 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: -153.8 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1455 38153..36699 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001694
References cited on this page View Complete Literature Guide for TRP3
1) Link, A. and Olson, M.  (1989) Personal Communication, Mortimer Map Edition 10
2) Paluh JL and Zalkin H  (1983) Isolation of Saccharomyces cerevisiae TRP3. J Bacteriol 153(1):345-9
3) Zalkin H, et al.  (1984) Nucleotide sequence of Saccharomyces cerevisiae genes TRP2 and TRP3 encoding bifunctional anthranilate synthase: indole-3-glycerol phosphate synthase. J Biol Chem 259(6):3985-92
4) Prantl F, et al.  (1985) Purification and characterization of the indole-3-glycerolphosphate synthase/anthranilate synthase complex of Saccharomyces cerevisiae. Eur J Biochem 146(1):95-100
5) Fantes PA, et al.  (1976) Free tryptophan pool and tryptophan biosynthetic enzymes in Saccharomyces cerevisiae. Arch Microbiol 107(2):207-14