CBT1/YKL208W Summary Help

Standard Name CBT1 1
Systematic Name YKL208W
Alias SOC1 2
Feature Type ORF, Verified
Description Protein involved in 5' RNA end processing; substrates include mitochondrial COB, 15S_rRNA, and RPM1 transcripts; may also have a role in 3' end processing of the COB pre-mRNA; displays genetic interaction with cell cycle-regulated kinase Dbf2p (1, 2, 3)
Name Description Cytochrome B Termination 1
Chromosomal Location
ChrXI:47157 to 47972 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All CBT1 GO evidence and references
  View Computational GO annotations for CBT1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
121 total interaction(s) for 118 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1

Genetic Interactions
  • Negative Genetic: 92
  • Positive Genetic: 27
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 271
Molecular Weight (Da) 31,156
Isoelectric Point (pI) 10.27
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:47157 to 47972 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..816 47157..47972 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001691
References cited on this page View Complete Literature Guide for CBT1
1) Rieger KJ, et al.  (1997) A novel nuclear gene, CBT1, essential for mitochondrial cytochrome b formation: terminal processing of mRNA and intron dependence. Curr Genet 32(3):163-74
2) Ellis T, et al.  (2005) CBT1 interacts genetically with CBP1 and the mitochondrially encoded cytochrome b gene and is required to stabilize the mature cytochrome b mRNA of Saccharomyces cerevisiae. Genetics 171(3):949-57
3) Grandin N and Charbonneau M  (1999) Dbf2 is implicated in a Cbt1-dependent pathway following a shift from glucose to galactose or non-fermentable carbon sources in Saccharomyces cerevisiae. Mol Gen Genet 261(2):402-7