YKT6/YKL196C Summary Help

YKT6 BASIC INFORMATION

Standard Name YKT6
Systematic Name YKL196C
Feature Type ORF, Verified
Description Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in trafficking to and within the Golgi, endocytic trafficking to the vacuole, and vacuolar fusion; membrane localization due to prenylation at the carboxy-terminus (1, 2, 3, 4)
GO Annotations All YKT6 GO evidence and references
    View Computational GO annotations for YKT6
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All YKT6 Phenotype details and references
Large-scale survey
conditional
null
Interactions YKT6 All interactions details and references
111 total interaction(s) for 44 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 16
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 35
  • Co-crystal Structure: 1
  • Co-fractionation: 1
  • Co-purification: 7
  • FRET: 1
  • Reconstituted Complex: 27
  • Two-hybrid: 5
Genetic Interactions
  • Dosage Rescue: 11
  • Synthetic Lethality: 2
  • Synthetic Rescue: 3
Sequence Information
ChrXI:75539 to 74937 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2004-02-13 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..603 75539..74937 2004-02-13 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001679

YKT6 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for YKT6

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for YKT6]

1) McNew JA, et al.  (1997) Ykt6p, a prenylated SNARE essential for endoplasmic reticulum-Golgi transport. J Biol Chem 272(28):17776-83
2) Lewis MJ and Pelham HR  (2002) A new yeast endosomal SNARE related to mammalian syntaxin 8. Traffic 3(12):922-9
3) Kweon Y, et al.  (2003) Ykt6p is a multifunctional yeast R-SNARE that is required for multiple membrane transport pathways to the vacuole. Mol Biol Cell 14(5):1868-81
4) Dietrich LE, et al.  (2004) The SNARE Ykt6 mediates protein palmitoylation during an early stage of homotypic vacuole fusion. EMBO J 23(1):45-53