Standard Name	YKT6 1
Systematic Name	YKL196C
Feature Type	ORF, Verified
Description	Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in trafficking to and within the Golgi, endocytic trafficking to the vacuole, and vacuolar fusion; membrane localization due to prenylation at the carboxy-terminus (2, 3, 4, 5)

Chromosomal Location	ChrXI:75534 to 74932 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for YKT6
Molecular Function
Manually curated	palmitoyltransferase activity (IDA) SNAP receptor activity (IDA)
Biological Process
Manually curated	intra-Golgi vesicle-mediated transport (TAS) vacuole fusion, non-autophagic (IMP) vesicle fusion (IDA)
Cellular Component
Manually curated	endosome (IDA) fungal-type vacuole (IDA) Golgi apparatus (IDA) membrane (IDA) SNARE complex (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
conditional	heat sensitivity: increased vegetative growth: decreased rate
null	inviable
repressible	endoplasmic reticulum morphology: abnormal
Large-scale survey
conditional	heat sensitivity: increased
null	haploinsufficient inviable toxin resistance: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	169 total interaction(s) for 63 unique genes/features.
Physical Interactions	Affinity Capture-MS: 33 Affinity Capture-RNA: 5 Affinity Capture-Western: 52 Co-crystal Structure: 1 Co-fractionation: 1 Co-localization: 1 Co-purification: 9 FRET: 1 PCA: 1 Reconstituted Complex: 31 Two-hybrid: 14
Genetic Interactions	Dosage Growth Defect: 2 Dosage Rescue: 11 Phenotypic Enhancement: 1 Synthetic Lethality: 2 Synthetic Rescue: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXI:75534 to 74932 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..603 75534..74932 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001679