ACP1/YKL192C Summary Help

Standard Name ACP1 1
Systematic Name YKL192C
Feature Type ORF, Verified
Description Mitochondrial matrix acyl carrier protein; involved in biosynthesis of octanoate, which is a precursor to lipoic acid; activated by phosphopantetheinylation catalyzed by Ppt2p (1, 2, 3)
Name Description Acyl Carrier Protein 1
Chromosomal Location
ChrXI:80537 to 80160 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All ACP1 GO evidence and references
  View Computational GO annotations for ACP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 10 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
reduction of function
Resources
23 total interaction(s) for 23 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-RNA: 6
  • Two-hybrid: 1

Genetic Interactions
  • Phenotypic Enhancement: 1
  • Positive Genetic: 2
  • Synthetic Lethality: 8

Resources
Expression Summary
histogram
Resources
Length (a.a.) 125
Molecular Weight (Da) 13,943
Isoelectric Point (pI) 4.64
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:80537 to 80160 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..378 80537..80160 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001675
References cited on this page View Complete Literature Guide for ACP1
1) Schneider R, et al.  (1995) Different respiratory-defective phenotypes of Neurospora crassa and Saccharomyces cerevisiae after inactivation of the gene encoding the mitochondrial acyl carrier protein. Curr Genet 29(1):10-7
2) Brody S, et al.  (1997) Mitochondrial acyl carrier protein is involved in lipoic acid synthesis in Saccharomyces cerevisiae. FEBS Lett 408(2):217-20
3) Stuible HP, et al.  (1998) A novel phosphopantetheine:protein transferase activating yeast mitochondrial acyl carrier protein. J Biol Chem 273(35):22334-9