HYM1/YKL189W Summary Help

Standard Name HYM1 1
Systematic Name YKL189W
Feature Type ORF, Verified
Description Component of the RAM signaling network; is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with Kic1p and Sog2p, localizes to sites of polarized growth during budding and during the mating response (1, 2)
Chromosomal Location
ChrXI:84704 to 85903 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All HYM1 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 6 genes
Resources
Classical genetics
null
unspecified
Large-scale survey
null
reduction of function
Resources
46 total interaction(s) for 33 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • PCA: 1
  • Two-hybrid: 10

Genetic Interactions
  • Dosage Rescue: 7
  • Negative Genetic: 1
  • Phenotypic Enhancement: 6
  • Positive Genetic: 1
  • Synthetic Growth Defect: 11
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 399
Molecular Weight (Da) 45,853
Isoelectric Point (pI) 8.52
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:84704 to 85903 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1200 84704..85903 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001672
References cited on this page View Complete Literature Guide for HYM1
1) Karos M and Fischer R  (1999) Molecular characterization of HymA, an evolutionarily highly conserved and highly expressed protein of Aspergillus nidulans. Mol Gen Genet 260(6):510-21
2) Nelson B, et al.  (2003) RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis. Mol Biol Cell 14(9):3782-803