MTR2/YKL186C Summary

MTR2 BASIC INFORMATION

Standard Name	MTR2 1, 2
Systematic Name	YKL186C
Feature Type	ORF, Verified
Description	mRNA transport regulator, essential nuclear protein; Mex67p and Mtr2p form a mRNA export complex which binds to RNA (1)
Name Description	Mrna TRansport 2

GO Annotations	All MTR2 GO evidence and references
	View Computational GO annotations for MTR2
Molecular Function
Manually curated	protein binding (IDA)
Biological Process
Manually curated	poly(A)+ mRNA export from nucleus (IMP, IPI) ribosomal large subunit export from nucleus (IGI, IMP)
Cellular Component
Manually curated	nuclear pore (IDA) nuclear RNA export factor complex (IPI)

Mutant Phenotype	All MTR2 Phenotype details and references
Classical genetics
conditional	poly(A)+ RNA accumulation: increased
Large-scale survey
null	inviable

Interactions	MTR2 All interactions details and references
	39 total interaction(s) for 22 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 1 Affinity Capture-Western: 10 Co-crystal Structure: 1 Reconstituted Complex: 6 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 5 Synthetic Lethality: 9 Synthetic Rescue: 1

Sequence Information

ChrXI:93303 to 92749 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-02-13 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
5' UTR intron	-167..-14	93470..93317	2007-04-04	2007-04-04
CDS	1..555	93303..92749	2004-02-13	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001669

MTR2 RESOURCES

Click on map for expanded view

SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for MTR2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for MTR2]

1)	Kadowaki T, et al. (1994) Nuclear mRNA accumulation causes nucleolar fragmentation in yeast mtr2 mutant. Mol Biol Cell 5(11):1253-63
2)	Kadowaki T, et al. (1994) Isolation and characterization of Saccharomyces cerevisiae mRNA transport-defective (mtr) mutants. J Cell Biol 126(3):649-59

SGD^tm pages Database Copyright © 1997-2010 The Board of Trustees of Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. The SGD project at Stanford University is supported by a Genome Research Resource Grant from the US National Human Genome Research Institute, part of the US National Institutes of Health.