Standard Name	LST4
Systematic Name	YKL176C
Feature Type	ORF, Verified
Description	Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface (1)
Name Description	Lethal with Sec Thirteen

Chromosomal Location	ChrXI:117986 to 115500 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for LST4
Molecular Function
Manually curated	protein transporter activity (IDA)
Biological Process
Manually curated	Golgi to plasma membrane transport (IDA) intracellular protein transport (IDA) protein transport (IDA) vesicle-mediated transport (IDA)
Cellular Component
Manually curated	vesicle coat (IDA)

Classical genetics
null	Ptr2p-GFP distribution: abnormal resistance to hydroxyurea: decreased
Large-scale survey
null	auxotrophy glycogen accumulation: increased chitin deposition: normal competitive fitness: decreased heat sensitivity: increased nutrient utilization: increased resistance to hydroxyurea: decreased resistance to tacrolimus (anhydrous) and tunicamycin: increased resistance to cycloheximide: decreased resistance to amitrole: decreased resistance to caffeine: decreased resistance to sirolimus: decreased resistance to acetic acid: decreased resistance to sodium arsenite: decreased resistance to quinine: decreased resistance to Calcofluor White: normal resistance to methyl methanesulfonate: decreased resistance to 1,4-dithiothreitol and tacrolimus (anhydrous): increased resistance to hygromycin B: decreased resistance to doxorubicin: decreased resistance to benzo[a]pyrene: decreased toxin resistance: decreased vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	144 total interaction(s) for 99 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 2
Genetic Interactions	Dosage Growth Defect: 1 Negative Genetic: 114 Phenotypic Suppression: 2 Positive Genetic: 9 Synthetic Growth Defect: 8 Synthetic Lethality: 5 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXI:117986 to 115500 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2487 117986..115500 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001659