PIR3/YKL163W Summary Help

PIR3 BASIC INFORMATION

Standard Name PIR3
Systematic Name YKL163W
Alias CCW8 1
Feature Type ORF, Verified
Description O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway (1, 2, 3, 4, 5, 6)
Name Description Protein containing Internal Repeats 7
GO Annotations All PIR3 GO evidence and references
    View Computational GO annotations for PIR3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All PIR3 Phenotype details and references
Large-scale survey
null
Interactions PIR3 All interactions details and references
4 total interaction(s) for 4 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Protein-RNA: 1

Genetic Interactions
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Sequence Information
ChrXI:144406 to 145383 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-02-13 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..978 144406..145383 2004-02-13 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001646

PIR3 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PIR3]

1) Mrsa V, et al.  (1997) Specific labelling of cell wall proteins by biotinylation. Identification of four covalently linked O-mannosylated proteins of Saccharomyces cerevisiae. Yeast 13(12):1145-54
2) Mrsa V and Tanner W  (1999) Role of NaOH-extractable cell wall proteins Ccw5p, Ccw6p, Ccw7p and Ccw8p (members of the Pir protein family) in stability of the Saccharomyces cerevisiae cell wall. Yeast 15(10A):813-20
3) Jung US and Levin DE  (1999) Genome-wide analysis of gene expression regulated by the yeast cell wall integrity signalling pathway. Mol Microbiol 34(5):1049-57
4) Yun DJ, et al.  (1997) Stress proteins on the yeast cell surface determine resistance to osmotin, a plant antifungal protein. Proc Natl Acad Sci U S A 94(13):7082-7
5) Doolin MT, et al.  (2001) Overlapping and distinct roles of the duplicated yeast transcription factors Ace2p and Swi5p. Mol Microbiol 40(2):422-32
6) Porter SE, et al.  (2002) The yeast pafl-rNA polymerase II complex is required for full expression of a subset of cell cycle-regulated genes. Eukaryot Cell 1(5):830-42
7) Toh-e A, et al.  (1993) Three yeast genes, PIR1, PIR2 and PIR3, containing internal tandem repeats, are related to each other, and PIR1 and PIR2 are required for tolerance to heat shock. Yeast 9(5):481-94