ELF1/YKL160W Summary Help

Standard Name ELF1 1
Systematic Name YKL160W
Feature Type ORF, Verified
Description Transcription elongation factor with a conserved zinc finger domain; implicated in the maintenance of proper chromatin structure in actively transcribed regions; deletion inhibits Brome mosaic virus (BMV) gene expression (1, 2)
Name Description ELongation Factor 2
Chromosomal Location
ChrXI:153269 to 153706 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ELF1 GO evidence and references
  View Computational GO annotations for ELF1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Classical genetics
unspecified
Large-scale survey
null
Resources
218 total interaction(s) for 164 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 10
  • Affinity Capture-RNA: 4
  • Affinity Capture-Western: 1
  • Biochemical Activity: 11
  • PCA: 2
  • Reconstituted Complex: 8

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 142
  • Phenotypic Enhancement: 2
  • Phenotypic Suppression: 2
  • Positive Genetic: 17
  • Synthetic Growth Defect: 7
  • Synthetic Lethality: 10
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 145
Molecular Weight (Da) 16,157
Isoelectric Point (pI) 4.32
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:153269 to 153706 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..438 153269..153706 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001643
References cited on this page View Complete Literature Guide for ELF1
1) Kushner DB, et al.  (2003) Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Proc Natl Acad Sci U S A 100(26):15764-9
2) Prather D, et al.  (2005) Identification and characterization of Elf1, a conserved transcription elongation factor in Saccharomyces cerevisiae. Mol Cell Biol 25(22):10122-35