PRR1/YKL116C Summary Help

Standard Name PRR1 1
Systematic Name YKL116C
Feature Type ORF, Verified
Description Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor (1, 2)
Name Description Pheromone Response Regulator 1
Chromosomal Location
ChrXI:222900 to 221344 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All PRR1 GO evidence and references
  View Computational GO annotations for PRR1
Molecular Function
Manually curated
High-throughput
Biological Process
Manually curated
High-throughput
Cellular Component
High-throughput
Regulators 3 genes
Resources
Classical genetics
overexpression
unspecified
Large-scale survey
null
unspecified
Resources
103 total interaction(s) for 75 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 30
  • Reconstituted Complex: 3
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Growth Defect: 4
  • Negative Genetic: 47
  • Positive Genetic: 7
  • Synthetic Lethality: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 518
Molecular Weight (Da) 58,955
Isoelectric Point (pI) 5.8
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:222900 to 221344 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1557 222900..221344 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001599
References cited on this page View Complete Literature Guide for PRR1
1) Burchett SA, et al.  (2001) Identification of novel pheromone-response regulators through systematic overexpression of 120 protein kinases in yeast. J Biol Chem 276(28):26472-8
2) Zhu H, et al.  (2000) Analysis of yeast protein kinases using protein chips. Nat Genet 26(3):283-9