YJU3/YKL094W Summary Help

Standard Name YJU3 1
Systematic Name YKL094W
Feature Type ORF, Verified
Description Monoglyceride lipase (MGL); functional ortholog of mammalian MGL, localizes to lipid particles and membranes, also member of the eukaryotic serine hydrolase family (2, 3, 4, 5)
Chromosomal Location
ChrXI:263349 to 264290 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All YJU3 GO evidence and references
  View Computational GO annotations for YJU3
Molecular Function
Manually curated
High-throughput
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
38 total interaction(s) for 29 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 1
  • Co-fractionation: 1
  • PCA: 7
  • Protein-peptide: 1

Genetic Interactions
  • Negative Genetic: 20
  • Phenotypic Enhancement: 2
  • Positive Genetic: 1
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 313
Molecular Weight (Da) 35,562
Isoelectric Point (pI) 8.5
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:263349 to 264290 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..942 263349..264290 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001577
References cited on this page View Complete Literature Guide for YJU3
1) Forrova H, et al.  (1992) Sequence of the novel essential gene YJU2 and two flanking reading frames located within a 3.2 kb EcoRI fragment from chromosome X of Saccharomyces cerevisiae. Yeast 8(5):419-22
2) Athenstaedt K, et al.  (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8
3) Baxter SM, et al.  (2004) Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast. Mol Cell Proteomics 3(3):209-25
4) McPartland JM, et al.  (2006) Evolutionary origins of the endocannabinoid system. Gene 370():64-74
5) Heier C, et al.  (2010) Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomycescerevisiae. Biochim Biophys Acta 1801(9):1063-1071