MBR1/YKL093W Summary Help

Standard Name MBR1 1
Systematic Name YKL093W
Feature Type ORF, Verified
Description Protein involved in mitochondrial functions and stress response; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; MBR1 has a paralog, ISF1, that arose from the whole genome duplication (1, 2, 3)
Name Description Mitochondrial Biogenesis Regulation 1
Chromosomal Location
ChrXI:264789 to 265808 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MBR1 GO evidence and references
  View Computational GO annotations for MBR1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
72 total interaction(s) for 61 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 14

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Rescue: 3
  • Negative Genetic: 43
  • Positive Genetic: 5
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 339
Molecular Weight (Da) 36,934
Isoelectric Point (pI) 6.35
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:264789 to 265808 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1020 264789..265808 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001576
References cited on this page View Complete Literature Guide for MBR1
1) Daignan-Fornier B, et al.  (1994) MBR1 and MBR3, two related yeast genes that can suppress the growth defect of hap2, hap3 and hap4 mutants. Mol Gen Genet 243(5):575-83
2) Reisdorf P, et al.  (1997) The MBR1 gene from Saccharomyces cerevisiae is activated by and required for growth under sub-optimal conditions. Mol Gen Genet 255(4):400-9
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61