SPC42/YKL042W Summary Help

Standard Name SPC42
Systematic Name YKL042W
Feature Type ORF, Verified
Description Central plaque component of spindle pole body (SPB); involved in SPB duplication, may facilitate attachment of the SPB to the nuclear membrane (1)
Name Description Spindle Pole Component
Chromosomal Location
ChrXI:358475 to 359566 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SPC42 GO evidence and references
  View Computational GO annotations for SPC42
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
overexpression
Large-scale survey
conditional
null
overexpression
reduction of function
Resources
100 total interaction(s) for 63 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 13
  • Affinity Capture-Western: 5
  • Biochemical Activity: 11
  • Co-crystal Structure: 1
  • Co-purification: 1
  • FRET: 8
  • PCA: 2
  • Reconstituted Complex: 2
  • Two-hybrid: 33

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 5
  • Phenotypic Suppression: 1
  • Positive Genetic: 1
  • Synthetic Growth Defect: 5
  • Synthetic Haploinsufficiency: 1
  • Synthetic Lethality: 7
  • Synthetic Rescue: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 363
Molecular Weight (Da) 42,271
Isoelectric Point (pI) 8.11
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:358475 to 359566 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1092 358475..359566 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001525
References cited on this page View Complete Literature Guide for SPC42
1) Bullitt E, et al.  (1997) The yeast spindle pole body is assembled around a central crystal of Spc42p. Cell 89(7):1077-86