Standard Name	AIM26 1
Systematic Name	YKL037W
Feature Type	ORF, Verified
Description	Putative protein of unknown function; null mutant is viable and displays elevated frequency of mitochondrial genome loss; null mutation confers sensitivity to tunicamycin and DTT (1, 2, 3, 4)
Name Description	Altered Inheritance rate of Mitochondria 1

Chromosomal Location	ChrXI:369365 to 369721 | ORF Map | GBrowse

	View Computational GO annotations for AIM26
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	mitochondrion degradation (IMP)
Cellular Component
Manually curated	mitochondrion (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
null	autophagy: decreased mitophagy: decreased viable
Large-scale survey
null	cell size: decreased glycogen accumulation: decreased competitive fitness: decreased dessication resistance: decreased inviable mitochondrial genome maintenance: abnormal mitophagy: decreased resistance to ethanol: decreased resistance to propan-1-ol: decreased resistance to caffeine: decreased resistance to sirolimus: decreased resistance to tunicamycin: decreased resistance to 1,4-dithiothreitol: decreased resistance to 4-chlorophenol: decreased resistance to dimethyl sulfoxide: decreased resistance to L-1,4-dithiothreitol: decreased resistance to acrolein: decreased resistance to benzo[a]pyrene: decreased respiratory growth: decreased rate stress resistance: decreased toxin resistance: decreased utilization of carbon source: decreased vegetative growth: decreased rate vegetative growth: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	19 total interaction(s) for 17 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 1 PCA: 2
Genetic Interactions	Negative Genetic: 1 Synthetic Growth Defect: 9 Synthetic Lethality: 5
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXI:369365 to 369721 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..357 369365..369721 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001520