GPX1/YKL026C Summary

GPX1 BASIC INFORMATION

Standard Name	GPX1
Systematic Name	YKL026C
Feature Type	ORF, Verified
Description	Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress (1, 2)
Name Description	Glutathione PeroXidase 1

GO Annotations	All GPX1 GO evidence and references
	View Computational GO annotations for GPX1
Molecular Function
Manually curated	glutathione peroxidase activity (IMP, ISS) phospholipid-hydroperoxide glutathione peroxidase activity (IDA, IMP)
Biological Process
Manually curated	response to oxidative stress (IMP)
Cellular Component
Manually curated	cellular_component unknown (ND)

Pathways	glutathione-glutaredoxin redox reactions

Mutant Phenotype	All GPX1 Phenotype details and references
Large-scale survey
null	viable

Interactions	GPX1 All interactions details and references
	3 total interaction(s) for 3 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 PCA: 1
Genetic Interactions	Synthetic Growth Defect: 1

Sequence Information

ChrXI:389526 to 389023 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2005-12-15 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..504	389526..389023	2005-12-15	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001509

GPX1 RESOURCES

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SGD ORF map	GBrowse

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Expression Summary

ADDITIONAL INFORMATION for GPX1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GPX1]

1)	Inoue Y, et al. (1999) Genetic analysis of glutathione peroxidase in oxidative stress response of Saccharomyces cerevisiae. J Biol Chem 274(38):27002-9
2)	Avery AM and Avery SV (2001) Saccharomyces cerevisiae expresses three phospholipid hydroperoxide glutathione peroxidases. J Biol Chem 276(36):33730-5

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