DAL7/YIR031C Summary Help

Standard Name DAL7 1
Systematic Name YIR031C
Alias MLS2 2 , MSL2
Feature Type ORF, Verified
Description Malate synthase; can accept butyryl-CoA as acyl-CoA donor in addition to traditional substrate acetyl-CoA; recycles glyoxylate generated during allantoin degradation; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation (1, 2, 3)
Name Description Degradation of Allantoin
Chromosomal Location
ChrIX:414679 to 413015 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 36.9 cM
Gene Ontology Annotations All DAL7 GO evidence and references
  View Computational GO annotations for DAL7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Pathways
Large-scale survey
null
Resources
8 total interaction(s) for 8 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Negative Genetic: 4
  • Positive Genetic: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 554
Molecular Weight (Da) 62,793
Isoelectric Point (pI) 6.47
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:414679 to 413015 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: 36.9 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1665 414679..413015 2011-02-03 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001470
References cited on this page View Complete Literature Guide for DAL7
1) Yoo HS, et al.  (1985) Identification of the ureidoglycolate hydrolase gene in the DAL gene cluster of Saccharomyces cerevisiae. Mol Cell Biol 5(9):2279-88
2) Fernandez E, et al.  (1993) Two structural genes are encoding malate synthase isoenzymes in Saccharomyces cerevisiae. FEBS Lett 320(3):271-5
3) Branduardi P, et al.  (2013) A novel pathway to produce butanol and isobutanol in Saccharomyces cerevisiae. Biotechnol Biofuels 6(1):68