YIL168W Summary

YIL168W Summary

Systematic Name	YIL168W
Alias	SDL1
Feature Type	pseudogene
Description	Open reading frame, unlikely to produce a functional protein in S288C; in closely related species and other S. cerevisiae strain backgrounds YIL168W and adjacent ORF, YIL167W, constitute a single ORF encoding L-serine dehydratase (1, 2, 3, 4)

Chromosomal Location	ChrIX:29032 to 29415 \| ORF Map \| GBrowse

Gene Ontology Annotations All YIL168W GO evidence and references


Molecular Function
Manually curated	L-serine ammonia-lyase activity (ISS)
Biological Process
Manually curated	serine family amino acid metabolic process (ISS)
Cellular Component
Manually curated	cellular_component unknown (ND)

Mutant phenotypes All YIL168W Phenotype evidence and references

Large-scale survey
null	competitive fitness: decreased resistance to amitrole: decreased resistance to cycloheximide: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY \| SCMD

interactions All YIL168W Interaction evidence and references

	10 total interaction(s) for 10 unique genes/features.
Genetic Interactions	Negative Genetic: 6 Positive Genetic: 3 Synthetic Lethality: 1
Resources	BioGRID \| YeastRC Two-Hybrid

Expression Summary


Resources	Genevestigator \| YMGV

Protein Information All YIL168W Protein evidence and references

Localization	YeastGFP
Phosphorylation	PhosphoGRID
Structure	SCOP \| YeastRC
Homologs	PDB Homologs

sequence information

ChrIX:29032 to 29415 | |

SGD ORF map

Last Update

Coordinates: 1994-12-10 | Sequence: 1994-12-10

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..384	29032..29415	1994-12-10	1994-12-10

Retrieve sequences

Analyze Sequence

S288C only	BLASTP \| ATCC/WashU Clones \| BLASTN \| Design Primers \| Restriction Fragment Map \| Restriction Fragment Sizes \| Six-Frame Translation
S288C vs. other species	Fungal Alignment \| BLASTN vs. fungi \| BLASTP vs. fungi \| Synteny Viewer

Resources

External Links	All Associated Seq \| Search all NCBI (Entrez) \| UniProtKB

Primary SGDID	S000001430

References cited on this page View Complete Literature Guide for YIL168W

1)	Churcher C, et al. (1997) The nucleotide sequence of Saccharomyces cerevisiae chromosome IX. Nature 387(6632 Suppl):84-7
2)	Seufert W (1990) Nucleotide sequence of the yeast SDH1 gene encoding a serine dehydratase homolog. Nucleic Acids Res 18(12):3653
3)	Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54
4)	Godard P, et al. (2007) Effect of 21 Different Nitrogen Sources on Global Gene Expression in the Yeast Saccharomyces cerevisiae. Mol Cell Biol 27(8):3065-86