BNR1/YIL159W Summary

BNR1 BASIC INFORMATION

Standard Name	BNR1 1
Systematic Name	YIL159W
Feature Type	ORF, Verified
Description	Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNI1 (2)
Name Description	BNi1 Related 1

GO Annotations	All BNR1 GO evidence and references
	View Computational GO annotations for BNR1
Molecular Function
Manually curated	cytoskeletal protein binding (TAS)
Biological Process
Manually curated	actin filament organization (TAS) axial cellular bud site selection (TAS) regulation of protein localization (IMP) response to osmotic stress (TAS)
Cellular Component
Manually curated	cellular bud neck contractile ring (TAS)

Mutant Phenotype	All BNR1 Phenotype details and references
Classical genetics
null	actin cytoskeleton morphology: abnormal budding pattern: abnormal chromosome/plasmid maintenance: decreased Bud6p-GFP distribution: abnormal
Large-scale survey
null	bud morphology: abnormal sporulation: normal viable

Interactions	BNR1 All interactions details and references
	68 total interaction(s) for 43 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Affinity Capture-RNA: 1 Protein-peptide: 1 Reconstituted Complex: 4 Two-hybrid: 22
Genetic Interactions	Dosage Rescue: 20 Phenotypic Enhancement: 5 Phenotypic Suppression: 1 Synthetic Growth Defect: 1 Synthetic Haploinsufficiency: 1 Synthetic Lethality: 8 Synthetic Rescue: 2

Sequence Information

ChrIX:41825 to 45952 | |

Last Update

Coordinates: 1994-12-10 | Sequence: 1994-12-10

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..4128	41825..45952	1994-12-10	1994-12-10

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001421

BNR1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for BNR1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for BNR1]

1)	Imamura H, et al. (1997) Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae. EMBO J 16(10):2745-55
2)	Dong Y, et al. (2003) Formin-dependent actin assembly is regulated by distinct modes of Rho signaling in yeast. J Cell Biol 161(6):1081-92

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