YIL151C Summary

YIL151C Summary

Reserved Name	ESL1 1 This name is reserved with SGD according to the Gene Naming Guidelines agreed upon by the yeast community. For more information about this reservation, please see the Locus History.
Systematic Name	YIL151C
Feature Type	ORF, Uncharacterized
Description	Putative protein of unknown function; predicted to contain a PINc domain; YIL151C has a paralog, ESL2, that arose from the whole genome duplication (2, 3)
Name Description	Est1A/B-Smg6/5-Like 1

Chromosomal Location	ChrIX:60694 to 57338 \| ORF Map \| GBrowse
	Note: this feature is encoded on the Crick strand.

Gene Ontology Annotations All YIL151C GO evidence and references

	View Computational GO annotations for YIL151C
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	biological_process unknown (ND)
Cellular Component
Manually curated	cellular_component unknown (ND)

Mutant phenotypes All YIL151C Phenotype evidence and references

Large-scale survey
null	competitive fitness: decreased
Resources	PROPHECY \| SCMD \| ScreenTroll \| Yeast Fitness Database

interactions All YIL151C Interaction evidence and references

	21 total interaction(s) for 21 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 2 Two-hybrid: 3
Genetic Interactions	Negative Genetic: 11
Resources	BioGRID \| BOND \| BioPIXIE \| CYC2008 (complexes) \| Complexome \| DIP \| DRYGIN \| GeneMANIA \| InterologFinder

Expression Summary


Resources	Expression Summary \| Cell cycle and metabolic oscillation \| Cell cycle transcript profile \| Cyclebase \| Genevestigator \| GermOnline \| SPELL \| YMGV \| YeastFunc

Protein Information All YIL151C Protein evidence and references

Localization	YeastRC \| YPL+ \| YeastGFP
Phosphorylation	PhosphoGRID \| PhosphoPep Database
Structure	GPMDB \| SCOP \| YeastRC
Homologs	Ashbya (AGD) \| Fungal Orthogroups Repository \| P-POD \| PDB Homologs \| PhylomeDB \| YGOB \| YOGY

sequence information

ChrIX:60694 to 57338 | |

Note: this feature is encoded on the Crick strand.

SGD ORF map

Last Update

Coordinates: 1994-12-10 | Sequence: 1994-12-10

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..3357	60694..57338	1994-12-10	1994-12-10

Retrieve sequences

Analyze Sequence

S288C only	BLASTP \| ATCC/WashU Clones \| BLASTN \| Design Primers \| Restriction Fragment Map \| Restriction Fragment Sizes \| Six-Frame Translation
S288C vs. other species	Fungal Alignment \| BLASTN vs. fungi \| BLASTP at NCBI \| BLASTP vs. fungi \| Synteny Viewer
S288C vs. other strains	Strain Alignment

Resources

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| Search all NCBI (Entrez) \| UniProtKB

Primary SGDID	S000001413

References cited on this page View Complete Literature Guide for

1)	Lai X, et al. (2008) DNA damage response functions of two Est1A/B-SMG6/5-Like (ESL) genes ()
2)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3)	Bleichert F, et al. (2006) The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. Proc Natl Acad Sci U S A 103(25):9464-9