CCT2/YIL142W Summary Help

Standard Name CCT2
Systematic Name YIL142W
Alias BIN3 , TCP2
Feature Type ORF, Verified
Description Subunit beta of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo (1, 2)
Name Description Chaperonin Containing TCP-1
Chromosomal Location
ChrIX:83302 to 84885 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All CCT2 GO evidence and references
  View Computational GO annotations for CCT2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
reduction of function
Large-scale survey
null
reduction of function
Resources
97 total interaction(s) for 76 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 60
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 3
  • Biochemical Activity: 1
  • Co-fractionation: 1
  • Co-purification: 1
  • Reconstituted Complex: 1

Genetic Interactions
  • Dosage Rescue: 14
  • Synthetic Lethality: 7
  • Synthetic Rescue: 6

Resources
Expression Summary
histogram
Resources
Length (a.a.) 527
Molecular Weight (Da) 57,203
Isoelectric Point (pI) 6
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:83302 to 84885 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1994-12-10 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1584 83302..84885 1994-12-10 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001404
References cited on this page View Complete Literature Guide for CCT2
1) Chen X, et al.  (1994) Two yeast genes with similarity to TCP-1 are required for microtubule and actin function in vivo. Proc Natl Acad Sci U S A 91(19):9111-5
2) Vinh DB and Drubin DG  (1994) A yeast TCP-1-like protein is required for actin function in vivo. Proc Natl Acad Sci U S A 91(19):9116-20