SIM1/YIL123W Summary Help

SIM1 BASIC INFORMATION

Standard Name SIM1 1
Systematic Name YIL123W
Feature Type ORF, Verified
Description Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) that may participate in DNA replication, promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated (2)
Name Description Start Independent of Mitosis 1
GO Annotations All SIM1 GO evidence and references
    View Computational GO annotations for SIM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All SIM1 Phenotype details and references
Large-scale survey
null
Interactions SIM1 All interactions details and references
12 total interaction(s) for 9 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Two-hybrid: 1
Genetic Interactions
  • Dosage Rescue: 8
  • Phenotypic Enhancement: 1
Sequence Information
ChrIX:128151 to 129578 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1994-12-10 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
5' UTR intron -489..-3 127662..128148 2007-04-04 2007-04-04
CDS 1..1428 128151..129578 1994-12-10 1994-12-10
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001385

SIM1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SIM1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SIM1]

1) Dahmann C, et al.  (1995) S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state. Curr Biol 5(11):1257-69
2) Mouassite M, et al.  (2000) The SUN family of Saccharomyces cerevisiae: the double knock-out of UTH1 and SIM1 promotes defects in nucleus migration and increased drug sensitivity. FEMS Microbiol Lett 182(1):137-41