Standard Name	MOB1 1
Systematic Name	YIL106W
Feature Type	ORF, Verified
Description	Component of the mitotic exit network; associates with and is required for the activation and Cdc15p-dependent phosphorylation of the Dbf2p kinase; required for cytokinesis and cell separation; component of the CCR4 transcriptional complex; relocalizes from cytoplasm to the nuclear periphery upon DNA replication stress (1, 2, 3, 4, 5, 6)
Name Description	Mps One Binder 1

Chromosomal Location	ChrIX:166415 to 167444 | ORF Map | GBrowse

	View Computational GO annotations for MOB1
Molecular Function
Manually curated	kinase regulator activity (IDA)
Biological Process
Manually curated	protein phosphorylation (IDA) regulation of exit from mitosis (TAS)
Cellular Component
Manually curated	cellular bud neck (IDA) spindle pole body (IDA)
High-throughput	cytoplasm (IDA) nuclear periphery (IDA)

Classical genetics
null	inviable Kic1p-GFP distribution: abnormal
Large-scale survey
null	inviable
overexpression	vegetative growth: decreased rate
repressible	chromosome/plasmid maintenance: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	98 total interaction(s) for 68 unique genes/features.
Physical Interactions	Affinity Capture-MS: 26 Affinity Capture-Western: 8 Biochemical Activity: 7 Co-crystal Structure: 1 Co-localization: 5 PCA: 2 Reconstituted Complex: 4 Two-hybrid: 9
Genetic Interactions	Dosage Growth Defect: 1 Dosage Lethality: 4 Dosage Rescue: 3 Negative Genetic: 10 Phenotypic Suppression: 2 Synthetic Growth Defect: 5 Synthetic Lethality: 9 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIX:166415 to 167444 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1999-11-17
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..20 166415..166434 2011-02-03 1999-11-17 Intron 21..105 166435..166519 2011-02-03 1999-11-17 CDS 106..1030 166520..167444 2011-02-03 1999-11-17
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS) Intron (21 - 105)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001368