PCI8/YIL071C Summary Help

PCI8 BASIC INFORMATION

Standard Name PCI8
Systematic Name YIL071C
Alias YIH1 , CSN11 , YIL071W
Feature Type ORF, Verified
Description Possible shared subunit of Cop9 signalosome (CSN) and eIF3, binds eIF3b subunit Prt1p, has possible dual functions in transcriptional and translational control, contains a PCI (Proteasome-COP9 signalosome (CSN)-eIF3) domain (1, 2)
Name Description Proteasome-COP9 signalosome (CSN)-eIF3 1
GO Annotations All PCI8 GO evidence and references
    View Computational GO annotations for PCI8
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All PCI8 Phenotype details and references
Classical genetics
null
Large-scale survey
null
overexpression
Interactions PCI8 All interactions details and references
27 total interaction(s) for 12 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 20
  • Affinity Capture-Western: 4
  • Reconstituted Complex: 2
Genetic Interactions
  • Phenotypic Suppression: 1
Sequence Information
ChrIX:229991 to 228657 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 1994-12-10 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1335 229991..228657 1994-12-10 1994-12-10
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001333

PCI8 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for PCI8

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
YIH1Nomenclature conflictDo not confuse PCI8/YIL071C with YIH1/YCR059C; both have been referred to as YIH1.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PCI8]

1) Shalev A, et al.  (2001) Saccharomyces cerevisiae protein Pci8p and human protein eIF3e/Int-6 interact with the eIF3 core complex by binding to cognate eIF3b subunits. J Biol Chem 276(37):34948-57
2) Maytal-Kivity V, et al.  (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep 3(12):1215-21