Standard Name	RHR2
Systematic Name	YIL053W
Alias	GPP1 1
Feature Type	ORF, Verified
Description	Constitutively expressed glycerol-1-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and osmotic stress; RHR2 has a paralog, HOR2, that arose from the whole genome duplication (1, 2, 3, 4, 5)
Name Description	Related to HoR2 6

Chromosomal Location	ChrIX:255115 to 255867 | ORF Map | GBrowse

	View Computational GO annotations for RHR2
Molecular Function
Manually curated	glycerol-1-phosphatase activity (IDA)
Biological Process
Manually curated	glycerol biosynthetic process (IMP) response to osmotic stress (TAS)
Cellular Component
High-throughput	cytoplasm (IDA) nucleus (IDA)

Pathways	glycerol biosynthesis

Classical genetics
null	chronological lifespan: decreased dessication resistance: decreased heat sensitivity: increased oxidative stress resistance: decreased
Large-scale survey
null	acid pH resistance: decreased glycogen accumulation: decreased competitive fitness: decreased dessication resistance: decreased hyperosmotic stress resistance: decreased resistance to sorbate: increased resistance to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO): decreased resistance to tunicamycin: decreased resistance to 1,4-dithiothreitol: decreased resistance to ethanol: decreased stress resistance: increased toxin resistance: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	123 total interaction(s) for 90 unique genes/features.
Physical Interactions	Affinity Capture-MS: 30 Affinity Capture-RNA: 7 Affinity Capture-Western: 1 Biochemical Activity: 3 PCA: 2 Reconstituted Complex: 2 Two-hybrid: 4
Genetic Interactions	Dosage Rescue: 5 Negative Genetic: 48 Phenotypic Enhancement: 1 Phenotypic Suppression: 1 Positive Genetic: 11 Synthetic Growth Defect: 5 Synthetic Lethality: 2 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIX:255115 to 255867 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 2006-01-24
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..753 255115..255867 2011-02-03 2006-01-24
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001315