PCL7/YIL050W Summary Help

Standard Name PCL7 1
Systematic Name YIL050W
Feature Type ORF, Verified
Description Pho85p cyclin of the Pho80p subfamily; forms a functional kinase complex with Pho85p which phosphorylates Mmr1p and is regulated by Pho81p; involved in glycogen metabolism, expression is cell-cycle regulated; PCL7 has a paralog, PCL6, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description Pho85 CycLin 1
Chromosomal Location
ChrIX:258913 to 259770 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PCL7 GO evidence and references
  View Computational GO annotations for PCL7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 12 genes
Resources
Large-scale survey
null
Resources
35 total interaction(s) for 19 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 10
  • Affinity Capture-Western: 5
  • Biochemical Activity: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 9

Genetic Interactions
  • Negative Genetic: 7
  • Positive Genetic: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 285
Molecular Weight (Da) 32,037
Isoelectric Point (pI) 4.89
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:258913 to 259770 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..858 258913..259770 2011-02-03 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001312
References cited on this page View Complete Literature Guide for PCL7
1) Measday V, et al.  (1997) A family of cyclin-like proteins that interact with the Pho85 cyclin-dependent kinase. Mol Cell Biol 17(3):1212-23
2) Lee M, et al.  (2000) Regulation of the Pcl7-Pho85 cyclin-cdk complex by Pho81. Mol Microbiol 38(2):411-22
3) Wang Z, et al.  (2001) The yeast cyclins Pc16p and Pc17p are involved in the control of glycogen storage by the cyclin-dependent protein kinase Pho85p. FEBS Lett 506(3):277-80
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61