Standard Name	PCL7
Systematic Name	YIL050W
Feature Type	ORF, Verified
Description	Pho85p cyclin of the Pho80p subfamily; forms a functional kinase complex with Pho85p which phosphorylates Mmr1p and is regulated by Pho81p; involved in glycogen metabolism, expression is cell-cycle regulated; PCL7 has a paralog, PCL6, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description	Pho85 CycLin 1

Chromosomal Location	ChrIX:258913 to 259770 | ORF Map | GBrowse

	View Computational GO annotations for PCL7
Molecular Function
Manually curated	cyclin-dependent protein serine/threonine kinase regulator activity (IDA)
Biological Process
Manually curated	regulation of cyclin-dependent protein serine/threonine kinase activity (IDA) regulation of glycogen biosynthetic process (IGI) regulation of glycogen catabolic process (IGI) regulation of protein stability (IMP)
Cellular Component
Manually curated	cyclin-dependent protein kinase holoenzyme complex (IPI) nucleus (IDA)

Large-scale survey
null	competitive fitness: decreased haploinsufficient resistance to tunicamycin: decreased resistance to cycloheximide: decreased resistance to 1,4-dithiothreitol: decreased resistance to dimethyl sulfoxide: decreased resistance to neomycin: decreased resistance to St. John's Wort extract: decreased stress resistance: increased toxin resistance: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	34 total interaction(s) for 18 unique genes/features.
Physical Interactions	Affinity Capture-MS: 9 Affinity Capture-Western: 5 Biochemical Activity: 1 Reconstituted Complex: 1 Two-hybrid: 9
Genetic Interactions	Negative Genetic: 7 Positive Genetic: 1 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIX:258913 to 259770 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..858 258913..259770 2011-02-03 1994-12-10
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001312