Standard Name	CBR1
Systematic Name	YIL043C
Alias	CBR5
Feature Type	ORF, Verified
Description	Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia (1, 2, 3, 4)
Name Description	Cytochrome b Reductase 2

Chromosomal Location	ChrIX:274926 to 274072 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for CBR1
Molecular Function
Manually curated	cytochrome-b5 reductase activity, acting on NAD(P)H (IDA)
Biological Process
Manually curated	biological_process unknown (ND)
Cellular Component
High-throughput	mitochondrial outer membrane (IDA) mitochondrion (IDA)

Large-scale survey
null	glycogen accumulation: increased competitive fitness: decreased resistance to benzo[a]pyrene: decreased toxin resistance: increased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	74 total interaction(s) for 54 unique genes/features.
Physical Interactions	Affinity Capture-MS: 29 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 PCA: 6
Genetic Interactions	Negative Genetic: 18 Phenotypic Enhancement: 1 Positive Genetic: 14 Synthetic Growth Defect: 1 Synthetic Lethality: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIX:274926 to 274072 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	This feature is contained within: 70321
	This feature is contained within: 70149
Last Update	Coordinates: 2011-02-03 | Sequence: 2006-01-23
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..855 274926..274072 2011-02-03 2006-01-23
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001305