CST6/YIL036W Summary

CST6 BASIC INFORMATION

Standard Name	CST6
Systematic Name	YIL036W
Alias	ACA2 , SHF1
Feature Type	ORF, Verified
Description	Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, activates transcription of genes involved in utilization of non-optimal carbon sources; involved in telomere maintenance (1, 2, 3)
Name Description	Chromosome STability 2

GO Annotations	All CST6 GO evidence and references
	View Computational GO annotations for CST6
Molecular Function
Manually curated	specific RNA polymerase II transcription factor activity (IDA)
High-throughput	sequence-specific DNA binding (IDA)
Biological Process
Manually curated	DNA metabolic process (IGI) transcription initiation from RNA polymerase II promoter (IDA)
Cellular Component
Manually curated	nucleus (IPI)

Mutant Phenotype	All CST6 Phenotype details and references
Large-scale survey
null	competitive fitness: decreased resistance to rapamycin: decreased resistance to wortmannin: decreased resistance to hydroxyurea: decreased respiratory growth: decreased rate respiratory growth: absent telomere length: decreased toxin resistance: increased viable
overexpression	cell cycle progression: abnormal vegetative growth: decreased

Interactions	CST6 All interactions details and references
	19 total interaction(s) for 19 unique genes/features.
Physical Interactions	Affinity Capture-MS: 9 Affinity Capture-RNA: 1 Biochemical Activity: 1 PCA: 1
Genetic Interactions	Dosage Rescue: 1 Phenotypic Enhancement: 1 Synthetic Growth Defect: 4 Synthetic Rescue: 1

Sequence Information

ChrIX:285665 to 287428 | |

Last Update

Coordinates: 1994-12-10 | Sequence: 1994-12-10

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1764	285665..287428	1994-12-10	1994-12-10

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001298

CST6 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for CST6

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CST6]

1)	Garcia-Gimeno MA and Struhl K (2000) Aca1 and Aca2, ATF/CREB activators in Saccharomyces cerevisiae, are important for carbon source utilization but not the response to stress. Mol Cell Biol 20(12):4340-9
2)	Ouspenski II, et al. (1999) New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability. Nucleic Acids Res 27(15):3001-8
3)	Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63

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