CFD1/YIL003W Summary Help

Standard Name CFD1 1
Systematic Name YIL003W
Alias DRE3 2
Feature Type ORF, Verified
Description Highly conserved iron-sulfur cluster binding protein; localized in the cytoplasm; forms a complex with Nbp35p that is involved in iron-sulfur protein assembly in the cytosol (1, 3)
Name Description Cytosolic Fe-S cluster Deficient 1
Chromosomal Location
ChrIX:349122 to 350003 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All CFD1 GO evidence and references
  View Computational GO annotations for CFD1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Classical genetics
null
Large-scale survey
null
reduction of function
Resources
19 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 4
  • Affinity Capture-Western: 6
  • Reconstituted Complex: 1
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Growth Defect: 2
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 293
Molecular Weight (Da) 31,922
Isoelectric Point (pI) 5.33
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:349122 to 350003 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..882 349122..350003 2011-02-03 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001265
References cited on this page View Complete Literature Guide for CFD1
1) Roy A, et al.  (2003) A novel eukaryotic factor for cytosolic Fe-S cluster assembly. EMBO J 22(18):4826-35
2) Woolford, J  (2001) personal communication
3) Netz DJ, et al.  (2007) The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol. Nat Chem Biol 3(5):278-86