TDA11/YHR159W Summary Help

Standard Name TDA11 1
Systematic Name YHR159W
Feature Type ORF, Uncharacterized
Description Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; potential Cdc28p substrate; null mutant is sensitive to expression of the top1-T722A allele (1, 2, 3)
Name Description Topoisomerase I Damage Affected 1
Chromosomal Location
ChrVIII:417549 to 419063 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All TDA11 GO evidence and references
  View Computational GO annotations for TDA11
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 61 genes
Resources
Large-scale survey
null
overexpression
Resources
23 total interaction(s) for 23 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 1
  • Two-hybrid: 5

Genetic Interactions
  • Dosage Growth Defect: 2
  • Dosage Lethality: 1
  • Negative Genetic: 11
  • Positive Genetic: 1
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 504
Molecular Weight (Da) 56,313
Isoelectric Point (pI) 8.6
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:417549 to 419063 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1515 417549..419063 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001202
References cited on this page View Complete Literature Guide for TDA11
1) Reid RJ, et al.  (2011) Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Genome Res 21(3):477-86
2) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
3) Ubersax JA, et al.  (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64