Standard Name	CHS7
Systematic Name	YHR142W
Feature Type	ORF, Verified
Description	Protein of unknown function; may be involved in chitin biosynthesis by regulation of Chs3p export from the ER; relocalizes from bud neck to ER upon DNA replication stress (1, 2)
Name Description	CHitin Synthase-related 1

Chromosomal Location	ChrVIII:383538 to 384488 | ORF Map | GBrowse

	View Computational GO annotations for CHS7
Molecular Function
Manually curated	unfolded protein binding (IMP)
Biological Process
Manually curated	ER to Golgi vesicle-mediated transport (IDA) fungal-type cell wall chitin biosynthetic process (IMP) protein folding (IMP)
Cellular Component
Manually curated	endoplasmic reticulum membrane (IDA)
High-throughput	cellular bud neck (IDA) cellular bud tip (IDA) endoplasmic reticulum (IDA) integral to membrane (ISM)

Classical genetics
null	chitin deposition: decreased Chs3p-GFP accumulation: abnormal resistance to Calcofluor white: increased viable
Large-scale survey
null	auxotrophy chitin deposition: decreased competitive fitness: decreased dessication resistance: decreased hyperosmotic stress resistance: decreased resistance to Calcofluor White: increased resistance to bleomycin: increased resistance to hydroxyurea: increased resistance to mycophenolic acid: increased resistance to tunicamycin: increased resistance to caspofungin: decreased resistance to caffeine: decreased resistance to dimethyl sulfoxide: decreased resistance to clioquinol: decreased sporulation efficiency: decreased stress resistance: decreased toxin resistance: increased vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	222 total interaction(s) for 115 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 2 Biochemical Activity: 1 PCA: 24
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 110 Synthetic Growth Defect: 24 Synthetic Lethality: 60
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVIII:383538 to 384488 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..951 383538..384488 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001184