CHS7/YHR142W Summary Help

Standard Name CHS7 1
Systematic Name YHR142W
Feature Type ORF, Verified
Description Protein of unknown function; may be involved in chitin biosynthesis by regulation of Chs3p export from the ER; relocalizes from bud neck to ER upon DNA replication stress (1, 2)
Name Description CHitin Synthase-related 1
Chromosomal Location
ChrVIII:383538 to 384488 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All CHS7 GO evidence and references
  View Computational GO annotations for CHS7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 5 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
266 total interaction(s) for 133 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 1
  • PCA: 24

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 151
  • Positive Genetic: 1
  • Synthetic Growth Defect: 25
  • Synthetic Lethality: 60

Resources
Expression Summary
histogram
Resources
Length (a.a.) 316
Molecular Weight (Da) 34,898
Isoelectric Point (pI) 5.62
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:383538 to 384488 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..951 383538..384488 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001184
References cited on this page View Complete Literature Guide for CHS7
1) Trilla JA, et al.  (1999) Chs7p, a new protein involved in the control of protein export from the endoplasmic reticulum that is specifically engaged in the regulation of chitin synthesis in Saccharomyces cerevisiae. J Cell Biol 145(6):1153-63
2) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76