EPT1/YHR123W Summary Help

Standard Name EPT1
Systematic Name YHR123W
Feature Type ORF, Verified
Description sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase; not essential for viability; EPT1 has a paralog, CPT1, that arose from the whole genome duplication (1, 2)
Chromosomal Location
ChrVIII:354815 to 356081 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All EPT1 GO evidence and references
  View Computational GO annotations for EPT1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 7 genes
Resources
Pathways
Large-scale survey
null
overexpression
Resources
83 total interaction(s) for 72 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Co-purification: 1
  • PCA: 19
  • Two-hybrid: 3

Genetic Interactions
  • Dosage Growth Defect: 1
  • Negative Genetic: 46
  • Positive Genetic: 10
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 391
Molecular Weight (Da) 44,559
Isoelectric Point (pI) 6.5
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:354815 to 356081 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..50 354815..354864 2011-02-03 1996-07-31
Intron 51..141 354865..354955 2011-02-03 1996-07-31
CDS 142..1267 354956..356081 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001165
References cited on this page View Complete Literature Guide for EPT1
1) Hjelmstad RH and Bell RM  (1988) The sn-1,2-diacylglycerol ethanolaminephosphotransferase activity of Saccharomyces cerevisiae. Isolation of mutants and cloning of the EPT1 gene. J Biol Chem 263(36):19748-57
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61