BZZ1/YHR114W Summary

BZZ1 BASIC INFORMATION

Standard Name	BZZ1 1
Systematic Name	YHR114W
Alias	LSB7 2
Feature Type	ORF, Verified
Description	SH3 domain protein implicated in the regulation of actin polymerization, able to recruit actin polymerization machinery through its SH3 domains, colocalizes with cortical actin patches and Las17p, interacts with type I myosins (2)

GO Annotations	All BZZ1 GO evidence and references
	View Computational GO annotations for BZZ1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	actin filament organization (IPI) endocytosis (IGI) response to salt stress (IGI, IPI)
Cellular Component
Manually curated	actin cortical patch (IDA)
High-throughput	cytoplasm (IDA) mating projection tip (IDA)

Mutant Phenotype	All BZZ1 Phenotype details and references
Large-scale survey
null	viable

Interactions	BZZ1 All interactions details and references
	118 total interaction(s) for 94 unique genes/features.
Physical Interactions	Affinity Capture-MS: 7 Affinity Capture-RNA: 1 Affinity Capture-Western: 4 Biochemical Activity: 3 PCA: 2 Protein-peptide: 1 Reconstituted Complex: 1 Two-hybrid: 94
Genetic Interactions	Phenotypic Enhancement: 1 Synthetic Growth Defect: 2 Synthetic Lethality: 2

Sequence Information

ChrVIII:338086 to 339987 | |

Last Update

Coordinates: 2005-11-07 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1902	338086..339987	2005-11-07	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001156

BZZ1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for BZZ1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for BZZ1]

1)	Tong AH, et al. (2002) A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules. Science 295(5553):321-4
2)	Soulard A, et al. (2002) Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro. Mol Cell Biol 22(22):7889-906

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