GEP4/YHR100C Summary Help

GEP4 BASIC INFORMATION

Standard Name GEP4 1
Systematic Name YHR100C
Feature Type ORF, Verified
Description Protein of unknown function required for respiratory growth; detected in highly purified mitochondria in high-throughput studies; null mutation confers sensitivity to tunicamycin and DTT and decreased levels of phosphatidylethanol (1, 2, 3, 4, 5)
Name Description GEnetic interactors of Prohibitins 1
GO Annotations All GEP4 GO evidence and references
    View Computational GO annotations for GEP4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Mutant Phenotype All GEP4 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions GEP4 All interactions details and references
7 total interaction(s) for 7 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Two-hybrid: 1
Genetic Interactions
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 1
Sequence Information
ChrVIII:314676 to 314119 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..558 314676..314119 2005-11-07 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001142

GEP4 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for GEP4

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GEP4]

1) Osman C, et al.  (2009) The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184(4):583-96
2) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
3) Steinmetz LM, et al.  (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
4) Reinders J, et al.  (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
5) Tan SX, et al.  (2009) Cu, Zn superoxide dismutase and NADP(H) homeostasis are required for tolerance of endoplasmic reticulum stress in Saccharomyces cerevisiae. Mol Biol Cell 20(5):1493-508