Standard Name	HXT1 1
Systematic Name	YHR094C
Alias	HOR4 2
Feature Type	ORF, Verified
Description	Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting; HXT1 has a paralog, HXT6, what arose from the whole genome duplication (3, 4, 5)
Name Description	HeXose Transporter 1

Chromosomal Location	ChrVIII:292625 to 290913 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 66.54 cM

	View Computational GO annotations for HXT1
Molecular Function
Manually curated	fructose transmembrane transporter activity (IMP) galactose transmembrane transporter activity (TAS) glucose transmembrane transporter activity (TAS) mannose transmembrane transporter activity (TAS) pentose transmembrane transporter activity (IMP)
Biological Process
Manually curated	glucose transport (IMP) mannose transport (IMP)
Cellular Component
Manually curated	plasma membrane (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
null	resistance to quinine: increased small molecule transport: decreased viable
Large-scale survey
null	competitive fitness: decreased lifespan: increased resistance to benzo[a]pyrene: decreased vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	117 total interaction(s) for 100 unique genes/features.
Physical Interactions	Affinity Capture-MS: 6 Co-fractionation: 2 PCA: 46 Protein-RNA: 1 Two-hybrid: 1
Genetic Interactions	Dosage Lethality: 1 Dosage Rescue: 7 Negative Genetic: 31 Phenotypic Enhancement: 7 Phenotypic Suppression: 2 Positive Genetic: 7 Synthetic Rescue: 6
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVIII:292625 to 290913 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 66.54 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1713 292625..290913 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB

Primary SGDID	S000001136