Standard Name	YNG2
Systematic Name	YHR090C
Alias	NBN1 , EAF4 1
Feature Type	ORF, Verified
Description	Subunit of NuA4, an essential histone acetyltransferase complex; positions Piccolo NuA4 for efficient acetylation of histone H4 or histone H2A; has similarity to the human tumor suppressor ING1 and its isoforms ING4 and ING5 (2, 3, 4, 5)
Name Description	Yeast homolog of mammalian Ing1

Chromosomal Location	ChrVIII:284625 to 283777 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for YNG2
Molecular Function
Manually curated	contributes_to histone acetyltransferase activity (IDA) methylated histone residue binding (IDA)
Biological Process
Manually curated	chromatin modification (IMP, IPI, ISS) DNA repair (IDA) histone acetylation (IDA)
Cellular Component
Manually curated	NuA4 histone acetyltransferase complex (IPI) nucleus (IDA) Piccolo NuA4 histone acetyltransferase complex (IDA)

Classical genetics
null	resistance to benomyl: decreased resistance to Calcofluor White: decreased resistance to methyl methanesulfonate: decreased resistance to sirolimus: decreased
overexpression	vegetative growth: normal
Large-scale survey
null	acid pH resistance: decreased resistance to boric acid: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	384 total interaction(s) for 283 unique genes/features.
Physical Interactions	Affinity Capture-Luminescence: 4 Affinity Capture-MS: 37 Affinity Capture-RNA: 1 Affinity Capture-Western: 25 Biochemical Activity: 9 Co-crystal Structure: 1 Co-purification: 1 Reconstituted Complex: 1 Two-hybrid: 2
Genetic Interactions	Dosage Growth Defect: 30 Dosage Lethality: 6 Negative Genetic: 23 Phenotypic Suppression: 1 Positive Genetic: 3 Synthetic Growth Defect: 93 Synthetic Lethality: 133 Synthetic Rescue: 14
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Mass Spec

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVIII:284625 to 283777 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..849 284625..283777 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001132