NAM8/YHR086W Summary Help

NAM8 BASIC INFORMATION

Standard Name NAM8
Systematic Name YHR086W
Alias MRE2 , MUD15
Feature Type ORF, Verified
Description RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of MER2 pre-mRNA (1, 2, 3)
Name Description Nuclear Accommodation of Mitochondria
GO Annotations All NAM8 GO evidence and references
    View Computational GO annotations for NAM8
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All NAM8 Phenotype details and references
Large-scale survey
null
overexpression
Interactions NAM8 All interactions details and references
129 total interaction(s) for 51 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 89
  • Affinity Capture-Western: 2
  • Co-purification: 1
  • Two-hybrid: 3
Genetic Interactions
  • Dosage Rescue: 4
  • Phenotypic Enhancement: 17
  • Phenotypic Suppression: 7
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 5
Sequence Information
ChrVIII:278155 to 279726 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1572 278155..279726 2005-11-07 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001128

NAM8 RESOURCES

Click on map for expanded view
SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for NAM8

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NAM8]

1) Nakagawa T and Ogawa H  (1997) Involvement of the MRE2 gene of yeast in formation of meiosis-specific double-strand breaks and crossover recombination through RNA splicing. Genes Cells 2(1):65-79
2) Puig O, et al.  (1999) Interaction of the U1 snRNP with nonconserved intronic sequences affects 5' splice site selection. Genes Dev 13(5):569-80
3) Ogawa H, et al.  (1995) Functions of the yeast meiotic recombination genes, MRE11 and MRE2. Adv Biophys 31:67-76