OSH3/YHR073W Summary Help

Standard Name OSH3 1
Systematic Name YHR073W
Feature Type ORF, Verified
Description Member of an oxysterol-binding protein family; this family has seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability (1)
Name Description OxySterol binding protein Homolog 1
Chromosomal Location
ChrVIII:242582 to 245572 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All OSH3 GO evidence and references
  View Computational GO annotations for OSH3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
Resources
60 total interaction(s) for 55 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 7
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1
  • Biochemical Activity: 7
  • PCA: 2
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 1
  • Negative Genetic: 17
  • Phenotypic Enhancement: 3
  • Positive Genetic: 9
  • Synthetic Growth Defect: 7
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 996
Molecular Weight (Da) 113,759
Isoelectric Point (pI) 9.1
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:242582 to 245572 | ORF Map | GBrowse
This feature contains embedded feature(s): YHR073C-B | YHR073W-A
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2991 242582..245572 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001115
References cited on this page View Complete Literature Guide for OSH3
1) Beh CT, et al.  (2001) Overlapping functions of the yeast oxysterol-binding protein homologues. Genetics 157(3):1117-40