TRM5/YHR070W Summary Help

Standard Name TRM5
Systematic Name YHR070W
Feature Type ORF, Verified
Description tRNA(m(1)G37)methyltransferase; methylates a tRNA base adjacent to the anticodon that has a role in prevention of frameshifting; highly conserved across Archaea, Bacteria, and Eukarya (1)
Name Description Transfer RNA Methyltransferase
Chromosomal Location
ChrVIII:234881 to 236380 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All TRM5 GO evidence and references
  View Computational GO annotations for TRM5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
conditional
Large-scale survey
conditional
null
overexpression
reduction of function
repressible
Resources
13 total interaction(s) for 12 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-RNA: 1
  • Two-hybrid: 2

Genetic Interactions
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 499
Molecular Weight (Da) 56,514
Isoelectric Point (pI) 9.35
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:234881 to 236380 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1500 234881..236380 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001112
References cited on this page View Complete Literature Guide for TRM5
1) Bjork GR, et al.  (2001) A primordial tRNA modification required for the evolution of life? EMBO J 20(1-2):231-9