SSF1/YHR066W Summary Help

SSF1 BASIC INFORMATION

Standard Name SSF1 1
Systematic Name YHR066W
Feature Type ORF, Verified
Description Constituent of 66S pre-ribosomal particles, required for ribosomal large subunit maturation; functionally redundant with Ssf2p; member of the Brix family (2, 3, 4)
Name Description Suppressor of ste4 (Four) 1
GO Annotations All SSF1 GO evidence and references
    View Computational GO annotations for SSF1
Molecular Function
Manually curated
Biological Process
Manually curated
High-throughput
Cellular Component
Manually curated
Mutant Phenotype All SSF1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions SSF1 All interactions details and references
184 total interaction(s) for 131 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 76
  • Affinity Capture-Western: 16
  • Two-hybrid: 1
Genetic Interactions
  • Dosage Rescue: 5
  • Phenotypic Enhancement: 35
  • Phenotypic Suppression: 46
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1
  • Synthetic Rescue: 2
Sequence Information
ChrVIII:229337 to 230698 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1362 229337..230698 2005-11-07 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001108

SSF1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SSF1

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
SPT16Nomenclature conflictSSF1 has been used in the literature to refer to both SPT16/YGL207W, which encodes a transcription elongation factor and SSF1/YHR066W, which encodes a rRNA binding protein.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SSF1]

1) Yu Y and Hirsch JP  (1995) An essential gene pair in Saccharomyces cerevisiae with a potential role in mating. DNA Cell Biol 14(5):411-8
2) Fatica A, et al.  (2002) Ssf1p prevents premature processing of an early pre-60S ribosomal particle. Mol Cell 9(2):341-51
3) Bogengruber E, et al.  (2003) Functional analysis in yeast of the Brix protein superfamily involved in the biogenesis of ribosomes. FEMS Yeast Res 3(1):35-43
4) Horsey EW, et al.  (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27