Standard Name	NCP1 (see Nomenclature conflict Note)
Systematic Name	YHR042W
Alias	CPR1 1
Feature Type	ORF, Verified
Description	NADP-cytochrome P450 reductase; involved in ergosterol biosynthesis; associated and coordinately regulated with Erg11p (2)

Chromosomal Location	ChrVIII:190543 to 192618 | ORF Map | GBrowse

	View Computational GO annotations for NCP1
Molecular Function
Manually curated	electron carrier activity (IDA)
Biological Process
Manually curated	ergosterol biosynthetic process (IMP)
Cellular Component
High-throughput	mitochondrial outer membrane (IDA) mitochondrion (IDA)

Classical genetics
null	filamentous growth: decreased invasive growth: absent resistance to enzymatic treatment: decreased vegetative growth: decreased viable
overexpression	resistance to tirapazamine: decreased
repressible	anaerobic growth: decreased rate
unspecified	resistance to ketoconazole: increased
Large-scale survey
null	inviable resistance to neothyonidioside: decreased toxin resistance: decreased
reduction of function	competitive fitness: increased telomere length: increased
repressible	mitochondrial morphology: abnormal
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	66 total interaction(s) for 56 unique genes/features.
Physical Interactions	Affinity Capture-MS: 18 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 Biochemical Activity: 1 PCA: 11 Reconstituted Complex: 1 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 14 Phenotypic Enhancement: 1 Positive Genetic: 6 Synthetic Growth Defect: 1 Synthetic Lethality: 10
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVIII:190543 to 192618 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2076 190543..192618 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001084