DAP2/YHR028C Summary Help

Standard Name DAP2 1
Systematic Name YHR028C
Alias DPP2
Feature Type ORF, Verified
Description Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p (2, 3)
Name Description Dipeptidyl AminoPeptidase 1
Chromosomal Location
ChrVIII:167434 to 164978 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All DAP2 GO evidence and references
  View Computational GO annotations for DAP2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 5 genes
Resources
Large-scale survey
null
overexpression
Resources
64 total interaction(s) for 49 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 3
  • Biochemical Activity: 4
  • Reconstituted Complex: 1

Genetic Interactions
  • Negative Genetic: 48
  • Positive Genetic: 1
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 818
Molecular Weight (Da) 93,404
Isoelectric Point (pI) 5.25
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:167434 to 164978 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2457 167434..164978 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001070
References cited on this page View Complete Literature Guide for DAP2
1) Suarez Rendueles P and Wolf DH  (1987) Identification of the structural gene for dipeptidyl aminopeptidase yscV (DAP2) of Saccharomyces cerevisiae. J Bacteriol 169(9):4041-8
2) Roberts CJ, et al.  (1989) Structure, biosynthesis, and localization of dipeptidyl aminopeptidase B, an integral membrane glycoprotein of the yeast vacuole. J Cell Biol 108(4):1363-73
3) Roberts CJ, et al.  (1992) Membrane protein sorting in the yeast secretory pathway: evidence that the vacuole may be the default compartment. J Cell Biol 119(1):69-83