OSH7/YHR001W Summary Help

Standard Name OSH7 1
Systematic Name YHR001W
Feature Type ORF, Verified
Description Oxysterol-binding protein; part of family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; OSH7 has a paralog, OSH6, that arose from the whole genome duplication (1, 2)
Name Description OxySterol binding protein Homolog 1
Chromosomal Location
ChrVIII:106055 to 107368 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All OSH7 GO evidence and references
  View Computational GO annotations for OSH7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Classical genetics
null
Large-scale survey
overexpression
Resources
41 total interaction(s) for 34 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 7
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Biochemical Activity: 2
  • PCA: 15
  • Reconstituted Complex: 1
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 1
  • Dosage Rescue: 3
  • Negative Genetic: 5
  • Phenotypic Enhancement: 1
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 437
Molecular Weight (Da) 49,804
Isoelectric Point (pI) 7.25
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:106055 to 107368 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1314 106055..107368 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001043
References cited on this page View Complete Literature Guide for OSH7
1) Beh CT, et al.  (2001) Overlapping functions of the yeast oxysterol-binding protein homologues. Genetics 157(3):1117-40
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61