Standard Name	SBP1 (see Nomenclature conflict Note)
Systematic Name	YHL034C
Alias	SSBR1 , SSB1 1
Feature Type	ORF, Verified
Description	Protein that binds eIF4G and has a role in repression of translation; has an RGG motif; found in cytoplasmic P bodies; found associated with small nucleolar RNAs snR10 and snR11; SBP1 has a paralog, RNP1, that arose from the whole genome duplication (1, 2, 3, 4, 5)

Chromosomal Location	ChrVIII:34077 to 33193 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for SBP1
Molecular Function
Manually curated	eukaryotic initiation factor 4G binding (IDA) RNA binding (ISS)
Biological Process
Manually curated	negative regulation of translation (IDA) negative regulation of translation in response to stress (IMP)
Cellular Component
Manually curated	cytoplasm (IDA) cytoplasmic mRNA processing body (IDA) nucleolus (IDA)

Classical genetics
null	vegetative growth: decreased rate
Large-scale survey
null	competitive fitness: decreased haploproficient hyperosmotic stress resistance: decreased resistance to cycloheximide: decreased resistance to L-canavanine: increased resistance to dimethyl sulfoxide: decreased vacuolar morphology: abnormal viable
overexpression	cell cycle progression: abnormal
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	1218 total interaction(s) for 1115 unique genes/features.
Physical Interactions	Affinity Capture-MS: 104 Affinity Capture-RNA: 1037 Affinity Capture-Western: 2 Biochemical Activity: 3 PCA: 1 Protein-RNA: 3 Reconstituted Complex: 3 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 5 Negative Genetic: 39 Positive Genetic: 13 Synthetic Growth Defect: 5 Synthetic Lethality: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVIII:34077 to 33193 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..885 34077..33193 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001026