RIM101/YHL027W Summary Help

Standard Name RIM101 1 (see Nomenclature conflict Note)
Systematic Name YHL027W
Alias RIM1
Feature Type ORF, Verified
Description Cys2His2 zinc-finger transcriptional repressor; involved in alkaline responsive gene repression as part of adaptation to a alkaline conditions; involved in cell wall assembly; required for alkaline pH-stimulated haploid invasive growth and sporulation; activated by alkaline-dependent proteolytic processing which results in removal of the C-terminal tail; similar to A. nidulans PacC (2, 3, 4)
Name Description Regulator of IME2 1
Chromosomal Location
ChrVIII:51111 to 52988 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RIM101 GO evidence and references
  View Computational GO annotations for RIM101
Molecular Function
Manually curated
High-throughput
Biological Process
Manually curated
Cellular Component
Manually curated
Regulatory Role
Binding motifs Predicted RIM101 Binding Site Locations
    Regulatory modules predicted: cellcycle (389)
    Resources
    Mutant phenotypes All RIM101 Phenotype evidence and references
    Classical genetics
    conditional
    null
    unspecified
    Large-scale survey
    null
    overexpression
    Resources
    interactions All RIM101 Interaction evidence and references
    333 total interaction(s) for 284 unique genes/features.
    Physical Interactions
    • Affinity Capture-RNA: 1
    • Affinity Capture-Western: 1
    • Biochemical Activity: 2
    • Two-hybrid: 4
    Genetic Interactions
    • Dosage Rescue: 1
    • Negative Genetic: 212
    • Phenotypic Enhancement: 5
    • Phenotypic Suppression: 22
    • Positive Genetic: 31
    • Synthetic Growth Defect: 40
    • Synthetic Lethality: 12
    • Synthetic Rescue: 2
    Resources
    Expression Summary
    histogram
    Resources
    Protein Information All RIM101 Protein evidence and references
    Localization
    Phosphorylation PhosphoGRID | PhosphoPep Database
    Structure
    Homologs
    sequence information
    ChrVIII:51111 to 52988 | ORF Map | GBrowse
    SGD ORF map
    Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
    Subfeature details
    Relative
    Coordinates    		 Chromosomal
    Coordinates    		 Most Recent Updates
    Coordinates Sequence
    CDS 1..1878 51111..52988 2011-02-03 1996-07-31
    Retrieve sequences
    Analyze Sequence
    S288C only
    S288C vs. other species
    S288C vs. other strains
    Resources
    External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
    Primary SGDIDS000001019

    NOMENCLATURE CONFLICT NOTE

    NameRelevanceDescription
    RIM1Nomenclature conflictBoth YHL027W/RIM101 and YCR028C-A/RIM1 have been referred to as RIM1.
    References cited on this page View Complete Literature Guide for RIM101
    1) Su SS and Mitchell AP  (1993) Identification of functionally related genes that stimulate early meiotic gene expression in yeast. Genetics 133(1):67-77
    2) Lamb TM and Mitchell AP  (2003) The transcription factor Rim101p governs ion tolerance and cell differentiation by direct repression of the regulatory genes NRG1 and SMP1 in Saccharomyces cerevisiae. Mol Cell Biol 23(2):677-86
    3) Penalva MA and Arst HN Jr  (2004) Recent advances in the characterization of ambient pH regulation of gene expression in filamentous fungi and yeasts. Annu Rev Microbiol 58():425-51
    4) Castrejon F, et al.  (2006) The RIM101 pathway contributes to yeast cell wall assembly and its function becomes essential in the absence of mitogen-activated protein kinase Slt2p. Eukaryot Cell 5(3):507-17
    5) Badis G, et al.  (2008) A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Mol Cell 32(6):878-87