RIM101/YHL027W Summary Help

Standard Name RIM101 1
Systematic Name YHL027W
Alias RIM1
Feature Type ORF, Verified
Description Cys2His2 zinc-finger transcriptional repressor; involved in alkaline responsive gene repression as part of adaptation to a alkaline conditions; involved in cell wall assembly; required for alkaline pH-stimulated haploid invasive growth and sporulation; activated by alkaline-dependent proteolytic processing which results in removal of the C-terminal tail; similar to A. nidulans PacC (2, 3, 4)
Name Description Regulator of IME2 1
Chromosomal Location
ChrVIII:51111 to 52988 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RIM101 GO evidence and references
Molecular Function
Manually curated
High-throughput
Biological Process
Manually curated
Cellular Component
Manually curated
Targets 71 genes
Regulators 5 genes
Resources
Classical genetics
conditional
null
unspecified
Large-scale survey
null
overexpression
Resources
430 total interaction(s) for 366 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Biochemical Activity: 2
  • Two-hybrid: 4

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 300
  • Phenotypic Enhancement: 5
  • Phenotypic Suppression: 22
  • Positive Genetic: 39
  • Synthetic Growth Defect: 40
  • Synthetic Lethality: 12
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 625
Molecular Weight (Da) 68,232
Isoelectric Point (pI) 7.18
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:51111 to 52988 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1878 51111..52988 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001019
References cited on this page View Complete Literature Guide for RIM101
1) Su SS and Mitchell AP  (1993) Identification of functionally related genes that stimulate early meiotic gene expression in yeast. Genetics 133(1):67-77
2) Lamb TM and Mitchell AP  (2003) The transcription factor Rim101p governs ion tolerance and cell differentiation by direct repression of the regulatory genes NRG1 and SMP1 in Saccharomyces cerevisiae. Mol Cell Biol 23(2):677-86
3) Penalva MA and Arst HN Jr  (2004) Recent advances in the characterization of ambient pH regulation of gene expression in filamentous fungi and yeasts. Annu Rev Microbiol 58():425-51
4) Castrejon F, et al.  (2006) The RIM101 pathway contributes to yeast cell wall assembly and its function becomes essential in the absence of mitogen-activated protein kinase Slt2p. Eukaryot Cell 5(3):507-17
5) Badis G, et al.  (2008) A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Mol Cell 32(6):878-87